Determination of nitrofurans metabolites residues in aquatic products by ultra-performance liquid chromatography–tandem mass spectrometry

Analytical methods Determination of Nitrofurans Metabolites Residues in Aquatic Products by Ul- tra-performance Liquid Chromatography-Tandem Mass Spectrometry

[Determination of metabolite residues of nitrofuran antibiotics in aquatic products by liquid chromatography-tandem mass spectrometry].

A method was developed for simultaneous qualitative and quantitative analysis of five metabolites of nitrofuran antibiotics, including 3-amino-2-oxazolidinone (AOZ), 5-morpholino-methyl-3-amino-2-oxazolidinone ( AMOZ ), semicarbazide ( SEM ), 1-aminohydantoin (AHD) and 3, 5-dinitrosalicylic acid hydrazide (DNSH) in aquatic products by liquid chromatography-tandem mass spectrometry (LC-MS/MS). T...

Determination of methylene blue residues in aquatic products by liquid chromatography-tandem mass spectrometry.

A method for the determination and confirmation of methylene blue (MB) in aquatic products was developed. Residues of MB were extracted from homogenized tissues with acetonitrile/sodium acetate buffer solution, and simply cleaned up with dichloromethane liquid/liquid extraction. After concentration and dissolution, the sample solutions were cleaned up by the neutral alumina and weak cation-exch...

Determination of Ractopamine Residues in Pigs by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry

Ractopamine hydrochloride is a xenobiotic that belongs to a large group of ß2-adrenergic agonist compounds. ß2-Agonists are used in human and veterinary medicine for treatment of lung diseases as bronchodilators, tocolytics and heart tonics (Courtheyn et al., 2002; Malucelli et al., 1994; Meyer & Rinke, 1991). Besides their legal use, these drugs are often misused as growth promoters, to improv...

Determination of Vitamin B12 in Dairy Products by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry

Vitamin B12 is a water-soluble molecule composed of a tetrapyrrolic complex with a cobalt atom at its centre. It is an essential regulatory element, synthesized only by bacteria; for this reason it is present only in food of animal origin and the daily requirement for humans is about 1 to 2 mg. Since milk and dairy products provide a significant dietary cobalamin intake, an ultra performance li...